Ethanol → HCID 11346746, compound

Participants

Reaction Steps

200 mg (0.733 mmol) of the compound of Example II are dissolved in 5 mL ethanol 70 mg (0.833 mmol) sodium bicarbonate and 70 mg (0.833 mmol) methyl propiolate are added at room temperature and the mixture is stirred for 24 h at room temperature. The solvent is evaporated under vacuum and the crude is stirred with ethyl acetate, filtered and dried to yield 77.3 mg (37% of th.) 4-benzoylpyrido[1,2-a]-benzimidazol-1(5H)-one.

Provenance & Evidence