HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1-(4-[4-(benzyloxy)phenyl]butyl}-1H-imidazol-2-yl)-1-ethanol → 4-[4-[2-(2-hydroxyethyl)-1H-imidazol-1-yl]butyl]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1-(4-[4-(benzyloxy)phenyl]butyl}-1H-imidazol-2-yl)-1-ethanol | HCID 22259313 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Product | 4-[4-[2-(2-hydroxyethyl)-1H-imidazol-1-yl]butyl]phenol | HCID 22259323 | 66.9% |
Reaction Steps
Using 2-(1-{4-[4-(benzyloxy)phenyl]butyl}-1H-imidazol-2-yl)-1-ethanol (10.67 g) and 10% palladium carbon (1.6 g), the same reaction as Reference Example 11-(v) was carried out to yield the titled compound (5.3 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06984653B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-0442f9a2410a443e806f82946b74729d |
| Source note | uspto-grants-2006_01 |