HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 22259345, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | Diethyl cyanophosphonate | HCID 76257 | — |
| Reactant | HCID 22259309 | HCID 22259309 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 22259345 | HCID 22259345 | — |
Reaction Steps
Using 3-[1-[4-[4-[(2-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,3-oxazol-4-yl)methoxy]phenyl]butyl]-1H-imidazol-2-yl]propionic acid (200 mg), pyrrolidine (0.174 ml), diethyl cyanophosphate (0.303 ml) and triethylamine (0.310 ml), the same reaction as Example 5-(ii) was carried out to yield the titled compound (86 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06984653B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-dfff3c07d1ae47df93bb5973bb73e0b5 |
| Source note | uspto-grants-2006_01 |