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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1610982Generated: October 31, 2026

Sodium hydride → HCID 22259300, compound

https://huagongshe.com/reaction/1610982

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
Reactant4-[4-[2-[(methylsulfonyl)methyl]-1H-imidazol-1-yl]butyl]phenolHCID 22259297—
ReactantHCID 22259326HCID 22259326—
ProductHCID 22259300HCID 2225930054.1%

Reaction Steps

Using 4-(chloromethyl)-2-[(E)-2-(2,4-dichlorophenyl)ethenyl]-1,3-oxazole (257 mg), 4-[4-[2-[(methylsulfonyl)methyl]-1H-imidazol-1-yl]butyl]phenol (250 mg) and 65% sodium hydride (35.9 mg), the same reaction as Example 11-(i) was carried out to yield the titled compound (246 mg) as a-colorless crystal powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06984653B2
Source datasetuspto-grants-2006_01
ORD IDord-ba7e9b06a958481685c48ea3a4cce1e0
Source noteuspto-grants-2006_01