HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4-methyl-2,3-dihydro-1H-inden-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 4-Methyl-1-indanone | HCID 4418431 | — |
| Solvent | MeOH tetrahydrofuran | HCID 21899815 | — |
| Product | 4-methyl-2,3-dihydro-1H-inden-1-ol | HCID 10986396 | 99% |
Reaction Steps
NaBH4 is added, in portions, at 0° C., to the solution of 4-methyl-1-indanone in THF/CH3OH. After 3 hours the mixture is poured into water and extracted with ether. After washing the organic extracts to neutrality and anhydrifying on Na2SO4, the solvent is evaporated under vacuum. 22.0 g of 4-methyl-1-indanol are obtained (yield=99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06984703B1 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-1306efb484a34773b025cb1886a8f508 |
| Source note | uspto-grants-2006_01 |