Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 16112Generated: October 26, 2026

(2S)-2-[[4'-[[(1,1-dimethylethyl)amino]carbonyl]-3'-fluoro-5-(trifluoromethyl) [1,1'-biphenyl]-2-yl]oxy]-propanoic acid → (2S)-2-[[5-chloro-4'-[[(1,1-dimethylethyl)amino]carbonyl]-3'-fluoro[1,1'-biphenyl]-2-yl]oxy]-propanoic acid

https://huagongshe.com/reaction/16112

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-2-[[4'-[[(1,1-dimethylethyl)amino]carbonyl]-3'-fluoro-5-(trifluoromethyl) [1,1'-biphenyl]-2-yl]oxy]-propanoic acidHCID 11539174—
Reactant(2S)-2-(2-borono-4-chlorophenoxy)-propanoic acidHCID 67277298—
Product(2S)-2-[[5-chloro-4'-[[(1,1-dimethylethyl)amino]carbonyl]-3'-fluoro[1,1'-biphenyl]-2-yl]oxy]-propanoic acidHCID 11538441—

Reaction Steps

The title compound was prepared using the product of example 33 step a) and the product of example 28 step c) by the method of example 32 step b).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07737135B2
Source datasetuspto-grants-2010_06
ORD IDord-dff6b5a0db1547c19bd0363b932ca948
Source noteuspto-grants-2010_06