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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611262Generated: October 26, 2026

5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione → 1-(Cyclobutyl)methyl-5-isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione

https://huagongshe.com/reaction/1611262

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedioneHCID 10493727—
ReactantCyclobutylmethyl 4-methylbenzenesulfonateHCID 13163931—
Product1-(Cyclobutyl)methyl-5-isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedioneHCID 1595770241%

Reaction Steps

5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione and (cyclobutyl)methyl para-toluenesulfonate were reacted by the same way with the example 1 to obtain the titled compound (147 mg, yield: 41.0%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06987114B1
Source datasetuspto-grants-2006_01
ORD IDord-9fa75aaa0402485fafc70c9260c76daf
Source noteuspto-grants-2006_01