Cyclobutylmethyl 4-methylbenzenesulfonate → HCID 9949835, compound

HRID 1611265Notes

Reaction equation

HRID 1611265 reaction equation
[CH2:1]([C:3]1[C:4](=[O:20])[NH:5][C:6](=[O:19])[NH:7][C:8]=1[C:9](=[O:18])[C:10]1[CH:15]=[C:14]([CH3:16])[CH:13]=[C:12]([CH3:17])[CH:11]=1)[CH3:2].C1(C)C=CC(S(O[CH2:31][CH:32]2[CH2:35][CH2:34][CH2:33]2)(=O)=O)=CC=1>>[CH:32]1([CH2:31][N:7]2[C:8]([C:9](=[O:18])[C:10]3[CH:11]=[C:12]([CH3:17])[CH:13]=[C:14]([CH3:16])[CH:15]=3)=[C:3]([CH2:1][CH3:2])[C:4](=[O:20])[NH:5][C:6]2=[O:19])[CH2:35][CH2:34][CH2:33]1

Participants

3

Reactant 2

HCID 13163931Cyclobutylmethyl 4-methylbenzenesulfonateHCID 222565796-(3,5-dimethylbenzoyl)-5-ethylpyrimidine-2,4(1H,3H)-dione

Product 1

HCID 9949835HCID 9949835, compoundYield 52.6%

Procedure

5-Ehtyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and (cyclobutyl)methyl para-toluenesulfonate were reacted by the same way with the example 1 to obtain the titled compound (179 mg, yield: 52.6%).

Sources & evidence

ORD record
ord-ddbddcbba3454e9ebab0c52cfd6421fc
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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