Cyclohexylmethyl 4-methylbenzenesulfonate → HCID 9885616, compound

HRID 1611271Notes

Reaction equation

HRID 1611271 reaction equation
[CH2:1]([C:3]1[C:4](=[O:20])[NH:5][C:6](=[O:19])[NH:7][C:8]=1[C:9](=[O:18])[C:10]1[CH:15]=[C:14]([CH3:16])[CH:13]=[C:12]([CH3:17])[CH:11]=1)[CH3:2].[C:21]1([CH3:38])[CH:26]=[CH:25][C:24](S(OCC2CCCCC2)(=O)=O)=[CH:23][CH:22]=1>>[CH:21]1([CH2:38][N:7]2[C:8]([C:9](=[O:18])[C:10]3[CH:11]=[C:12]([CH3:17])[CH:13]=[C:14]([CH3:16])[CH:15]=3)=[C:3]([CH2:1][CH3:2])[C:4](=[O:20])[NH:5][C:6]2=[O:19])[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1

Participants

3

Reactant 2

HCID 11807699Cyclohexylmethyl 4-methylbenzenesulfonateHCID 222565796-(3,5-dimethylbenzoyl)-5-ethylpyrimidine-2,4(1H,3H)-dione

Product 1

HCID 9885616HCID 9885616, compoundYield 63.2%

Procedure

5-Ethyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and (cyclohexyl)methyl para-toluenesulfonate were reacted by the same way with the example 1 to obtain the titled compound (233 mg, yield: 63.2%).

Sources & evidence

ORD record
ord-87e74f23d979457fbaee0bde9d670cee
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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