Cyclohexylmethyl 4-methylbenzenesulfonate → HCID 15957706, compound

HRID 1611272Notes

Reaction equation

HRID 1611272 reaction equation
[CH:1]([C:4]1[C:5](=[O:21])[NH:6][C:7](=[O:20])[NH:8][C:9]=1[C:10](=[O:19])[C:11]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]([CH3:18])[CH:12]=1)([CH3:3])[CH3:2].[C:22]1([CH3:39])[CH:27]=[CH:26][C:25](S(OCC2CCCCC2)(=O)=O)=[CH:24][CH:23]=1>>[CH:22]1([CH2:39][N:8]2[C:9]([C:10](=[O:19])[C:11]3[CH:12]=[C:13]([CH3:18])[CH:14]=[C:15]([CH3:17])[CH:16]=3)=[C:4]([CH:1]([CH3:3])[CH3:2])[C:5](=[O:21])[NH:6][C:7]2=[O:20])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 11807699Cyclohexylmethyl 4-methylbenzenesulfonateHCID 222565826-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione

Product 1

HCID 15957706HCID 15957706, compoundYield 55.4%

Procedure

5-Isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and (cyclohexyl)methyl para-toluenesulfonate were reacted by the same way with the example 1 to obtain the titled compound (212 mg, yield: 55.4%).

Sources & evidence

ORD record
ord-95085ce6ee184c97a8cf0c7f749776e4
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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