3-Methoxybenzyl bromide → HCID 15957709, compound

HRID 1611279Notes

Reaction equation

HRID 1611279 reaction equation
[CH2:1]([C:3]1[C:4](=[O:19])[NH:5][C:6](=[O:18])[NH:7][C:8]=1[S:9][C:10]1[CH:15]=[C:14]([CH3:16])[CH:13]=[C:12]([CH3:17])[CH:11]=1)[CH3:2].[O:20]([C:22]1[CH:23]=[C:24]([CH:27]=[CH:28][CH:29]=1)[CH2:25]Br)[CH3:21]>>[CH3:21][O:20][C:22]1[CH:23]=[C:24]([CH:27]=[CH:28][CH:29]=1)[CH2:25][N:7]1[C:8]([S:9][C:10]2[CH:11]=[C:12]([CH3:17])[CH:13]=[C:14]([CH3:16])[CH:15]=2)=[C:3]([CH2:1][CH3:2])[C:4](=[O:19])[NH:5][C:6]1=[O:18]

Participants

3

Reactant 2

HCID 40672073-Methoxybenzyl bromideHCID 104927276-(3,5-dimethylphenyl)sulfanyl-5-ethyl-1H-pyrimidine-2,4-dione

Product 1

HCID 15957709HCID 15957709, compoundYield 44.1%

Procedure

5-Ethyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione and 3-methoxylbenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (175 mg, yield: 44.1%).

Sources & evidence

ORD record
ord-ff15869105d149ca9c0550144130b049
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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