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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611295Generated: October 27, 2026

Benzonitrile, 3-(bromomethyl)- → 1-(3-Cyanobenzyl)-5-isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione

https://huagongshe.com/reaction/1611295

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzonitrile, 3-(bromomethyl)-HCID 97249—
Reactant5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedioneHCID 10493727—
Product1-(3-Cyanobenzyl)-5-isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedioneHCID 1595772843.4%

Reaction Steps

5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione and 3-cyanobenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (176 mg, yield: 43.4%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06987114B1
Source datasetuspto-grants-2006_01
ORD IDord-7dca7790237a4744abad872bd34cc67e
Source noteuspto-grants-2006_01