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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611298Generated: October 30, 2026

Benzonitrile, 3-(bromomethyl)- → 1-(3-Cyanobenzyl)-5-ethyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione

https://huagongshe.com/reaction/1611298

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzonitrile, 3-(bromomethyl)-HCID 97249—
Reactant6-(3,5-dimethylbenzoyl)-5-ethylpyrimidine-2,4(1H,3H)-dioneHCID 22256579—
Product1-(3-Cyanobenzyl)-5-ethyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedioneHCID 1595773153.4%

Reaction Steps

5-Ethyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and 3-cyanobenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (207 mg, yield: 53.4%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06987114B1
Source datasetuspto-grants-2006_01
ORD IDord-8133c4a6c26f40549656c7505828ccf1
Source noteuspto-grants-2006_01