3,5-Dimethoxybenzyl Bromide → HCID 15957736, compound

HRID 1611306Notes

Reaction equation

HRID 1611306 reaction equation
[CH2:1]([C:3]1[C:4](=[O:19])[NH:5][C:6](=[O:18])[NH:7][C:8]=1[S:9][C:10]1[CH:15]=[C:14]([CH3:16])[CH:13]=[C:12]([CH3:17])[CH:11]=1)[CH3:2].[CH3:20][O:21][C:22]1[CH:23]=[C:24]([CH:27]=[C:28]([O:30][CH3:31])[CH:29]=1)[CH2:25]Br>>[CH3:31][O:30][C:28]1[CH:27]=[C:24]([CH:23]=[C:22]([O:21][CH3:20])[CH:29]=1)[CH2:25][N:7]1[C:8]([S:9][C:10]2[CH:11]=[C:12]([CH3:17])[CH:13]=[C:14]([CH3:16])[CH:15]=2)=[C:3]([CH2:1][CH3:2])[C:4](=[O:19])[NH:5][C:6]1=[O:18]

Participants

3

Reactant 2

HCID 12744903,5-Dimethoxybenzyl BromideHCID 104927276-(3,5-dimethylphenyl)sulfanyl-5-ethyl-1H-pyrimidine-2,4-dione

Product 1

HCID 15957736HCID 15957736, compoundYield 59.1%

Procedure

5-Ethyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione and 3,5-dimethoxybenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (252 mg, yield: 59.1%).

Sources & evidence

ORD record
ord-f87f0625cd4f4da4bd60260faaa403d6
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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