HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Bromomethyl)-1,4-difluorobenzene → 1-(2,5-Difluorobenzyl)-5-isopropyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Bromomethyl)-1,4-difluorobenzene | HCID 522830 | — |
| Reactant | 5-Isopropyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione | HCID 22256578 | — |
| Product | 1-(2,5-Difluorobenzyl)-5-isopropyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione | HCID 15957750 | 41.2% |
Reaction Steps
5-Isopropyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and 2,5-difluorobenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (165 mg, yield: 41.2%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06987114B1 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-defa87fc247a4fddb941488f17a08db8 |
| Source note | uspto-grants-2006_01 |