5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione → HCID 15957756, compound

HRID 1611331Notes

Reaction equation

HRID 1611331 reaction equation
[CH:1]([C:4]1[C:5](=[O:20])[NH:6][C:7](=[O:19])[NH:8][C:9]=1[S:10][C:11]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]([CH3:18])[CH:12]=1)([CH3:3])[CH3:2].[Cl:21][C:22]1[CH:23]=[C:24]([CH:27]=[C:28]([Cl:30])[CH:29]=1)[CH2:25]Br>>[Cl:21][C:22]1[CH:23]=[C:24]([CH:27]=[C:28]([Cl:30])[CH:29]=1)[CH2:25][N:8]1[C:9]([S:10][C:11]2[CH:12]=[C:13]([CH3:18])[CH:14]=[C:15]([CH3:17])[CH:16]=2)=[C:4]([CH:1]([CH3:3])[CH3:2])[C:5](=[O:20])[NH:6][C:7]1=[O:19]

Participants

3

Reactant 2

HCID 104937275-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedioneHCID 125839781-(Bromomethyl)-3,5-dichlorobenzene

Product 1

HCID 15957756HCID 15957756, compoundYield 55.6%

Procedure

5-isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione and 3,5-dichlorobenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (250 mg, yield: 55.6%).

Sources & evidence

ORD record
ord-1618209d08e1438997af8d5a6b083f12
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

Loading…