5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione → HCID 15957757, compound

HRID 1611332Notes

Reaction equation

HRID 1611332 reaction equation
[CH2:1]([C:3]1[C:4](=[O:19])[NH:5][C:6](=[O:18])[NH:7][C:8]=1[O:9][C:10]1[CH:15]=[C:14]([CH3:16])[CH:13]=[C:12]([CH3:17])[CH:11]=1)[CH3:2].[Cl:20][C:21]1[CH:22]=[C:23]([CH:26]=[C:27]([Cl:29])[CH:28]=1)[CH2:24]Br>>[Cl:20][C:21]1[CH:22]=[C:23]([CH:26]=[C:27]([Cl:29])[CH:28]=1)[CH2:24][N:7]1[C:8]([O:9][C:10]2[CH:11]=[C:12]([CH3:17])[CH:13]=[C:14]([CH3:16])[CH:15]=2)=[C:3]([CH2:1][CH3:2])[C:4](=[O:19])[NH:5][C:6]1=[O:18]

Participants

3

Reactant 2

HCID 109232665-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedioneHCID 125839781-(Bromomethyl)-3,5-dichlorobenzene

Product 1

HCID 15957757HCID 15957757, compoundYield 52.7%

Procedure

5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and 3,5-dichlorobenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (220 mg, yield: 52.7%).

Sources & evidence

ORD record
ord-5321b80d413844cd9015de8c9d00415a
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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