3,5-Dibromobenzyl bromide → HCID 15957766, compound

HRID 1611340Notes

Reaction equation

HRID 1611340 reaction equation
[CH:1]([C:4]1[C:5](=[O:21])[NH:6][C:7](=[O:20])[NH:8][C:9]=1[C:10](=[O:19])[C:11]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]([CH3:18])[CH:12]=1)([CH3:3])[CH3:2].[Br:22][C:23]1[CH:24]=[C:25]([CH:28]=[C:29]([Br:31])[CH:30]=1)[CH2:26]Br>>[Br:22][C:23]1[CH:24]=[C:25]([CH:28]=[C:29]([Br:31])[CH:30]=1)[CH2:26][N:8]1[C:9]([C:10](=[O:19])[C:11]2[CH:12]=[C:13]([CH3:18])[CH:14]=[C:15]([CH3:17])[CH:16]=2)=[C:4]([CH:1]([CH3:3])[CH3:2])[C:5](=[O:21])[NH:6][C:7]1=[O:20]

Participants

3

Reactant 2

HCID 1434273,5-Dibromobenzyl bromideHCID 222565826-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione

Product 1

HCID 15957766HCID 15957766, compoundYield 75.2%

Procedure

5-Isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and 3,5-dibromobenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (402 mg, yield: 75.2%).

Sources & evidence

ORD record
ord-89ea1c3fb63e47d2bc6971e41cfded5b
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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