2-(Chloromethyl)anthraquinone → 6-(3,5-Dimethylphenoxy)-1-[(9,10-dioxo-2-anthryl)methyl]-5-ethyl-pyrimidine-2,4-dione

HRID 1611349Notes

Reaction equation

HRID 1611349 reaction equation
[CH2:1]([C:3]1[C:4](=[O:19])[NH:5][C:6](=[O:18])[NH:7][C:8]=1[O:9][C:10]1[CH:15]=[C:14]([CH3:16])[CH:13]=[C:12]([CH3:17])[CH:11]=1)[CH3:2].Cl[CH2:21][C:22]1[CH:35]=[CH:34][C:33]2[C:32](=[O:36])[C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[C:25](=[O:37])[C:24]=2[CH:23]=1>>[CH:23]1[C:24]2[C:25](=[O:37])[C:26]3[C:31](=[CH:30][CH:29]=[CH:28][CH:27]=3)[C:32](=[O:36])[C:33]=2[CH:34]=[CH:35][C:22]=1[CH2:21][N:7]1[C:8]([O:9][C:10]2[CH:11]=[C:12]([CH3:17])[CH:13]=[C:14]([CH3:16])[CH:15]=2)=[C:3]([CH2:1][CH3:2])[C:4](=[O:19])[NH:5][C:6]1=[O:18]

Participants

3

Reactant 2

HCID 3443112-(Chloromethyl)anthraquinoneHCID 109232665-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione

Product 1

HCID 159577816-(3,5-Dimethylphenoxy)-1-[(9,10-dioxo-2-anthryl)methyl]-5-ethyl-pyrimidine-2,4-dioneYield 36.3%

Procedure

5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and 2-chloromethyl anthraquinone were reacted by the same way with the example 1 to obtain the titled compound (175 mg, yield: 36.3%).

Sources & evidence

ORD record
ord-79a9ab1ef7504e9aade60dfdb2f81e0f
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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