Methyl 2-(Bromomethyl)-3-Furoate → HCID 15957821, compound

HRID 1611384Notes

Reaction equation

HRID 1611384 reaction equation
[CH2:1]([C:3]1[C:4](=[O:19])[NH:5][C:6](=[O:18])[NH:7][C:8]=1[O:9][C:10]1[CH:15]=[C:14]([CH3:16])[CH:13]=[C:12]([CH3:17])[CH:11]=1)[CH3:2].Br[CH2:21][C:22]1[O:23][CH:24]=[CH:25][C:26]=1[C:27]([O:29][CH3:30])=[O:28]>>[CH3:30][O:29][C:27]([C:26]1[CH:25]=[CH:24][O:23][C:22]=1[CH2:21][N:7]1[C:8]([O:9][C:10]2[CH:11]=[C:12]([CH3:17])[CH:13]=[C:14]([CH3:16])[CH:15]=2)=[C:3]([CH2:1][CH3:2])[C:4](=[O:19])[NH:5][C:6]1=[O:18])=[O:28]

Participants

3

Reactant 2

HCID 2736827Methyl 2-(Bromomethyl)-3-FuroateHCID 109232665-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione

Product 1

HCID 15957821HCID 15957821, compoundYield 36.4%

Procedure

5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and 2-bromomethyl-3-methoxycarbonylfurane were reacted by the same way with the example 1 to obtain the titled compound (139 mg, yield: 36.4%).

Sources & evidence

ORD record
ord-a548a77c92aa45c7a9026ac6927c0a19
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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