Chloroacetone → HCID 15957825, compound
Reaction equation
[CH2:1]([C:3]1[C:4](=[O:19])[NH:5][C:6](=[O:18])[NH:7][C:8]=1[O:9][C:10]1[CH:15]=[C:14]([CH3:16])[CH:13]=[C:12]([CH3:17])[CH:11]=1)[CH3:2].Cl[CH2:21][C:22](=[O:24])[CH3:23]>>[CH2:21]([N:7]1[C:8]([O:9][C:10]2[CH:11]=[C:12]([CH3:17])[CH:13]=[C:14]([CH3:16])[CH:15]=2)=[C:3]([CH2:1][CH3:2])[C:4](=[O:19])[NH:5][C:6]1=[O:18])[C:22]([CH3:23])=[O:24]Participants
3
Procedure
5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and chloroacetone were reacted by the same way with the example 1 to obtain the titled compound (172 mg, yield: 54%).
Sources & evidence
- ORD record
- ord-3100a8f3351e4255a48fea27b00a444e
- Source dataset
- uspto-grants-2006_01
- Patent number
- US06987114B1
Reaction notes
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