Chloroacetone → HCID 15957827, compound

HRID 1611390Notes

Reaction equation

HRID 1611390 reaction equation
[CH2:1]([C:3]1[C:4](=[O:20])[NH:5][C:6](=[O:19])[NH:7][C:8]=1[C:9](=[O:18])[C:10]1[CH:15]=[C:14]([CH3:16])[CH:13]=[C:12]([CH3:17])[CH:11]=1)[CH3:2].Cl[CH2:22][C:23](=[O:25])[CH3:24]>>[CH2:22]([N:7]1[C:8]([C:9](=[O:18])[C:10]2[CH:11]=[C:12]([CH3:17])[CH:13]=[C:14]([CH3:16])[CH:15]=2)=[C:3]([CH2:1][CH3:2])[C:4](=[O:20])[NH:5][C:6]1=[O:19])[C:23]([CH3:24])=[O:25]

Participants

3

Reactant 2

HCID 6571ChloroacetoneHCID 222565796-(3,5-dimethylbenzoyl)-5-ethylpyrimidine-2,4(1H,3H)-dione

Product 1

HCID 15957827HCID 15957827, compoundYield 44%

Procedure

5-Ethyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and chloroacetone were reacted by the same way with the example 1 to obtain the titled compound (145 mg, yield: 44%).

Sources & evidence

ORD record
ord-a8b749f085b3482092cc0dcce53fb6fe
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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