Chloroacetone → HCID 15957828, compound

HRID 1611391Notes

Reaction equation

HRID 1611391 reaction equation
[CH:1]([C:4]1[C:5](=[O:21])[NH:6][C:7](=[O:20])[NH:8][C:9]=1[C:10](=[O:19])[C:11]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]([CH3:18])[CH:12]=1)([CH3:3])[CH3:2].Cl[CH2:23][C:24](=[O:26])[CH3:25]>>[CH2:23]([N:8]1[C:9]([C:10](=[O:19])[C:11]2[CH:12]=[C:13]([CH3:18])[CH:14]=[C:15]([CH3:17])[CH:16]=2)=[C:4]([CH:1]([CH3:3])[CH3:2])[C:5](=[O:21])[NH:6][C:7]1=[O:20])[C:24]([CH3:25])=[O:26]

Participants

3

Reactant 2

HCID 6571ChloroacetoneHCID 222565826-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione

Product 1

HCID 15957828HCID 15957828, compoundYield 45%

Procedure

5-Isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and chloroacetone were reacted by the same way with the example 1 to obtain the titled compound (155 mg, yield: 45%).

Sources & evidence

ORD record
ord-44b8f5eaedb7440b95b5374efb5f4789
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

Loading…