HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[2,6-Dichloro-4-(phenylmethoxy)phenoxy]butan-1-ol → 3,5-Dichloro-4-(4-hydroxybutoxy)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[2,6-Dichloro-4-(phenylmethoxy)phenoxy]butan-1-ol | HCID 22257135 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 3,5-Dichloro-4-(4-hydroxybutoxy)phenol | HCID 22257131 | — |
Reaction Steps
This compound was prepared in a manner analogous to that of Step A of this example, using 12.2 grams (0.036 mole) of 4-[2,6-dichloro-4-(phenylmethoxy)phenoxy]butan-1-ol and 0.5 gram (catalyst) of 10% palladium on carbon and a theoretical amount of hydrogen gas in a Parr Hydrogenator. The yield of the subject compound was 9.3 grams. The NMR spectrum was consistent with the proposed structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06987194B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-68940b919345426ba63d0c73b4754ffe |
| Source note | uspto-grants-2006_01 |