Sodium Hydroxide → L-Leucine
Reaction equation
Cl.[NH2:2][C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][CH:5]([CH3:7])[CH3:6].[OH-].[Na+]>O>[NH2:2][C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][CH:5]([CH3:7])[CH3:6]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A similar dispersion was prepared with the use of Pluronic F-68 as stabilizer. An amount of 0.152 grams of leucine hydrochloride was added to 0.852 grams of nanostructured reverse bicontinuous cubic phase material as above, and an upper phase consisting of 0.08 grams of F-68, 1.0 gram of 1 M sodium hydroxide, and 3.0 grams of water was overlaid on the nanostrucrured reverse bicontinuous cubic phase material and sonicated. Again, a milky-white dispersion of leucine-coated microparticles was formed, where this time the F-68 amphiphilic block copolymer surfactant coated the outer (leucine-based) surface of the particles.
Workup
- customsonicated
Sources & evidence
- ORD record
- ord-ace8c45e57b743f49c65a4ce914f1beb
- Source dataset
- uspto-grants-2006_01
- Patent number
- US06989195B2
Reaction notes
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