Diisopropylethylamine → HCID 22254178, compound

Participants

Reaction Conditions

Reaction Steps

To 22 mgs of 2-(2,4-dichlorophenyl)-4-fluoro-1-nitrobenzene in N,N-dimethylformamide was added 1–5 mgs of [2-(methylaminoethyl](5-nitro(2-pyridyl))-amine and 30 μl of N,N-diisopropylethylamine, and the mixture was heated to 85° C. over-night. After partitioning the mixture between ethyl acetate and water the organic layer was concentrated and dried (MgSO4) and recrystallized to yield 6 mgs of N-(2′,4′-dichloro-6-nitro-1,1′-biphenyl-3-yl)-N-methyl-N′-(5-nitropyridin-2-yl)ethane-1,2-diamine.

Provenance & Evidence