Isatoic Anhydride → 4-(4-(2-Aminobenzoyl)aminophenyl)butyric acid

HRID 1611870Notes

Reaction equation

[C:1]12[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=1)[NH:6]C(=O)[O:4][C:2]2=O.[NH2:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][CH2:22][C:23]([OH:25])=[O:24])=[CH:16][CH:15]=1>>[NH2:6][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:1]=1[C:2]([NH:13][C:14]1[CH:15]=[CH:16][C:17]([CH2:20][CH2:21][CH2:22][C:23]([OH:25])=[O:24])=[CH:18][CH:19]=1)=[O:4]

Participants

Reactant 2

HCID 8359Isatoic Anhydride

HCID 270494-(4-Aminophenyl)butanoic acid

Product 1

HCID 222514094-(4-(2-Aminobenzoyl)aminophenyl)butyric acid

Procedure

4-(4-(2-aminobenzoyl)aminophenyl)butyric acid was prepared using Method F starting from isatoic anhydride and 4-(4aminophenyl)butyric acid.

Sources & evidence

ORD record: ord-a25fa0ff8fbd43908e0aafabf631d9d2
Source dataset: uspto-grants-2006_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06991798B1

Reaction notes

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