HCID 54166420, compound → HCID 54089172, compound

Participants

Reaction Steps

A suspension of 2,4-di(N-benzylpiperazinyl)-6-hydrazino pyrimidine (19.7 g, 43 mmol) and Raney Ni (5 g) in EtOAc (250 mL) was shaken in a Parr hydrogenator at 50 psi H2 for 16 hours. The resulting suspension was filtered through celite and the filtrate was concentrated to give 18 g (94%) of the title compound as a foam. 1H NMR (CDCl3) δ 2.47 (m, 8H, piperazine), 3.51 (m, 8H, piperazine), 3.77 (m, 4H, CH2), 4.30 (bs, 2H, NH2), 5.04 (s, 1H, C5H), 7.3 (m, 10H, Ar).

Provenance & Evidence