Sodium Hydroxide → HCID 17908962, compound

HRID 1611988Notes

Reaction equation

HRID 1611988 reaction equation
[CH2:1]1[N:6]([CH2:7][CH2:8][C:9]([O:11]CC)=[O:10])[CH2:5][CH2:4][N:3]2[CH2:14][CH2:15][CH2:16][CH2:17][CH:2]12.[OH-].[Na+]>C(O)C>[CH2:1]1[N:6]([CH2:7][CH2:8][C:9]([OH:11])=[O:10])[CH2:5][CH2:4][N:3]2[CH2:14][CH2:15][CH2:16][CH2:17][CH:2]12

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22252333HCID 22252333, compound

Product 1

HCID 17908962HCID 17908962, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 6.0 g of the compound obtained in Step A in 50 ml of ethanol and 25 ml of a 1M sodium hydroxide solution is heated for 5 hours at 50° C. and then concentrated to dryness in vacuo and dried in the presence of P2O5 to yield the expected compound.

Workup

  1. concentrationconcentrated to dryness in vacuo
  2. dry with materialdried in the presence of P2O5

Sources & evidence

ORD record
ord-06f90fd1226e4416bd3aeb2c9ea56286
Source dataset
uspto-grants-2006_01
Patent number
US06992085B2

Reaction notes

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