Cesium fluoride → HCID 22252387, compound

Participants

Reaction Steps

A suspension of 1.78 g of the compound obtained in Step A, 0.835 g of CsF and 1.1 g of ethyl 4-bromobutyrate in 80 ml of dimethylformamide is stirred, under argon, for 3 hours. After removal of the solvent by distillation, the residue is taken up in a mixture of water/dichloromethane, decanted and then dried over sodium sulphate. Chromatography over silica gel eluted with dichloromethane enables the expected product to be isolated.

Provenance & Evidence