HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromovaleryl chloride → HCID 22252386, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromovaleryl chloride | HCID 521173 | — |
| Reactant | HCID 10072789 | HCID 10072789 | — |
| Catalyst | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 22252386 | HCID 22252386 | — |
Reaction Steps
A solution of 8.5 g of the compound obtained in Step A, 3.2 ml of 5-bromopentanoyl chloride, 0.3 g of Pd2(dba)3 and 250 ml of toluene is refluxed for 6 hours, and then cooled and evaporated in vacuo. The residue is purified by chromatography over silica gel eluted with dichloromethane, enabling the expected product to be isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992085B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-cacb20fdd933418fbe595f1f586c6532 |
| Source note | uspto-grants-2006_01 |