HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 70152762, compound → HCID 18973210, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 70152762 | HCID 70152762 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 18973210 | HCID 18973210 | 68.5% |
Reaction Steps
A mixture of Compound 25 (3.96 g, 10.8 mmol) and 10% palladium on carbon (600 mg) in abs. methanol (100 mL) was hydrogenated at 1 atm for 12 hr. The hydrogen was replaced with nitrogen, the reaction was filtered and concentrated in vacuo. Chromatography of the residue on silica gel (elution with 20% ethyl acetate:hexanes) provided 2.72 g of Compound 26.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05726184 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-10ff625fe5984e5b87fd676cfad5e889 |
| Source note | uspto-grants-1998_03 |