1,4-Dibromobutane → 4-(4-Bromobutoxy)-2-methoxybenzonitrile
Reaction equation
[OH:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[C:4]([O:10][CH3:11])[CH:3]=1.[Br:12][CH2:13][CH2:14][CH2:15][CH2:16]Br>>[Br:12][CH2:13][CH2:14][CH2:15][CH2:16][O:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[C:4]([O:10][CH3:11])[CH:3]=1Participants
3
Procedure
The procedure is as for Example 53, Step A, using as substrate 4-hydroxy-2-methoxy-benzonitrile and 1,4-dibromobutane.
Sources & evidence
- ORD record
- ord-c2fc0405d08f4199a9ac411fb605928a
- Source dataset
- uspto-grants-2006_01
- Patent number
- US06992085B2
Reaction notes
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