Sodium Hydroxide → HCID 22252722, compound

HRID 1612021Notes

Reaction equation

HRID 1612021 reaction equation
C([O:3][C:4]([CH2:6][CH2:7][CH2:8][O:9][C:10]1[C:11]([Se:24][C:25]2[CH:35]=[CH:34][C:28]([C:29]([O:31]CC)=[O:30])=[CH:27][N:26]=2)=[CH:12][C:13]2[C:14]([CH3:23])([CH3:22])[CH2:15][CH2:16][C:17]([CH3:21])([CH3:20])[C:18]=2[CH:19]=1)=[O:5])C.[OH-].[Na+]>C(O)C>[C:4]([CH2:6][CH2:7][CH2:8][O:9][C:10]1[C:11]([Se:24][C:25]2[CH:35]=[CH:34][C:28]([C:29]([OH:31])=[O:30])=[CH:27][N:26]=2)=[CH:12][C:13]2[C:14]([CH3:23])([CH3:22])[CH2:15][CH2:16][C:17]([CH3:21])([CH3:20])[C:18]=2[CH:19]=1)([OH:5])=[O:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22252752HCID 22252752, compound

Product 1

HCID 22252722HCID 22252722, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a manner similar to that of Example 2, by reaction of 340 mg (0.62 mmol) of ethyl 6-[3-(3-ethoxycarbonylpropoxy)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthylselanyl]nicotinate with 250 mg (62.2 mmol) of sodium hydroxide in ethanol (10 ml), 211 mg (69%) of a white powder are obtained. m.p.: 177° C.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-b7c0666d3f084154b9303a65649a3c7a
Source dataset
uspto-grants-2006_01
Patent number
US06992094B1

Reaction notes

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