Sodium Hydroxide → HCID 22252764, compound

HRID 1612023Notes

Reaction equation

HRID 1612023 reaction equation
[C:1]([CH2:4][CH2:5][CH2:6][O:7][C:8]1[C:9]([Se:22][C:23]2[CH:33]=[CH:32][C:26]([C:27]([O:29]CC)=[O:28])=[CH:25][CH:24]=2)=[CH:10][C:11]2[C:12]([CH3:21])([CH3:20])[CH2:13][CH2:14][C:15]([CH3:19])([CH3:18])[C:16]=2[CH:17]=1)([OH:3])=[O:2].[OH-].[Na+]>C1COCC1.C(O)C>[C:1]([CH2:4][CH2:5][CH2:6][O:7][C:8]1[C:9]([Se:22][C:23]2[CH:24]=[CH:25][C:26]([C:27]([OH:29])=[O:28])=[CH:32][CH:33]=2)=[CH:10][C:11]2[C:12]([CH3:21])([CH3:20])[CH2:13][CH2:14][C:15]([CH3:19])([CH3:18])[C:16]=2[CH:17]=1)([OH:3])=[O:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22252762HCID 22252762, compound

Product 1

HCID 22252764HCID 22252764, compound

Reagents, catalysts & solvents 1

HCID 21873804Tetrahydrofuran ethanolSolvent

Procedure

In manner similar to that of Example 2, by reaction of 250 mg (0.46 mmol) of ethyl 4-[3-(3-carboxypropoxy)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthylselanyl]benzoate with 183 mg (4.6 mmol) of sodium hydroxide in a THF/ethanol mixture (5 ml/5 ml), 172 mg (76%) of a white powder are obtained. m.p.: 230° C.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-30ad01b34e5541c6b368a08d7e6f1ede
Source dataset
uspto-grants-2006_01
Patent number
US06992094B1

Reaction notes

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