Sodium Hydroxide → HCID 22252760, compound

HRID 1612027Notes

Reaction equation

HRID 1612027 reaction equation
C([O:4][CH2:5][CH2:6][O:7][C:8]1[C:9]([Se:22][C:23]2[CH:33]=[CH:32][C:26]([C:27]([O:29]CC)=[O:28])=[CH:25][N:24]=2)=[CH:10][C:11]2[C:12]([CH3:21])([CH3:20])[CH2:13][CH2:14][C:15]([CH3:19])([CH3:18])[C:16]=2[CH:17]=1)(=O)C.[OH-].[Na+]>C1COCC1.C(O)C>[OH:4][CH2:5][CH2:6][O:7][C:8]1[C:9]([Se:22][C:23]2[CH:33]=[CH:32][C:26]([C:27]([OH:29])=[O:28])=[CH:25][N:24]=2)=[CH:10][C:11]2[C:12]([CH3:21])([CH3:20])[CH2:13][CH2:14][C:15]([CH3:18])([CH3:19])[C:16]=2[CH:17]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22252758HCID 22252758, compound

Product 1

HCID 22252760HCID 22252760, compound

Reagents, catalysts & solvents 1

HCID 21873804Tetrahydrofuran ethanolSolvent

Procedure

In a manner similar to that of Example 2, by reaction of 419 mg (0.81 mmol) of ethyl 6-[3-(2-acetoxyethoxy)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthylselanyl]nicotinate with 320 mg (8 mmol) of sodium hydroxide in a THF/ethanol mixture (4 ml/4 ml), 273 mg (75%) of a white powder are obtained. m.p.: 170° C.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-4139114ee3904c319a731611a7bdb452
Source dataset
uspto-grants-2006_01
Patent number
US06992094B1

Reaction notes

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