HCID 23594024, compound → HCID 23594015, compound

Participants

Reaction Steps

A solution of 2-(1-methoxynaphthalen-2-yl)-3-nitrobenzoic acid, methyl ester, (1.52 g, 4.5 mM) in triphenyl phosphite (7.19 g, 6.1 mL, 22.5 mM) was heated at 160° C. for 19 h under a nitrogen atmosphere. The mixture was cooled to room temperature and dried azeotropically in vacuo with toluene, then purified by column chromatography on silica gel (elution with gradient hexane/ethyl acetate) to afford 0.37 g (27%) of the title compound 11-methoxy-5H-benzo[b]carbazole-1-carboxylic acid, methyl ester as a yellow solid (MP 190–196° C., MW 305.34).

Provenance & Evidence