Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2,3,4-Tetrahydro-1-naphthylamine → 3,6-dimethyl-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyrazin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2,3,4-Tetrahydro-1-naphthylamine | HCID 18066 | — |
| 반응물 | 3-Chloro-2,5-dimethylpyrazine | HCID 66771 | — |
| 반응물 | (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol | HCID 58583341 | — |
| 생성물 | 3,6-dimethyl-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyrazin-2-amine | HCID 22147387 | — |
반응 단계
Following the procedure for the preparation of (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol but substituting 1,2,3,4-tetrahydronaphthalen-1-amine and 3-chloro-2,5-dimethylpyrazine, and making non-critical variations provided the title compound as a oil: 1H NMR (CDCl3) δ 1.91, 2.11, 2.31, 2.40, 2.87, 4.50, 5.16, 7.21, 7.35, 7.62; MS (ESI+) for C16H19N3 m/z 254.4 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06992087B2 |
| 출처 데이터셋 | uspto-grants-2006_01 |
| ORD ID | ord-9cc0a2cf76634c579ced5cf17e584894 |
| 출처 메모 | uspto-grants-2006_01 |