5-methyl-6,7-dihydrobenzofuran-4(5H)-one → 5-Methyl-4,5,6,7-tetrahydro-1-benzofuran-4-amine

Participants

Role	Name	HCID	Charge
Reactant	5-methyl-6,7-dihydrobenzofuran-4(5H)-one	HCID 13817690	—
Reactant	4,5,6,7-Tetrahydro-1-benzofuran-4-amine	HCID 18525171	—
Product	5-Methyl-4,5,6,7-tetrahydro-1-benzofuran-4-amine	HCID 23593714	—

Reaction Steps

Following the procedure for the preparation of 4,5,6,7-tetrahydro-1-benzofuran-4-amine but substituting 5-methyl-6,7-dihydro-1-benzofuran-4(5H)-one and making non-critical variations provided the title compound as a oil: MS (EI) m/z (rel. intensity) 151 (M+, 64), 151 (64), 134 (86), 110 (83), 109 (99), 108 (55), 88 (56), 86 (87), 84 (92), 80 (76), 51 (67). HRMS (FAB) calcd for C9H13NO+H 152.1075, found 152.1066.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06992087B2
Source dataset	uspto-grants-2006_01
ORD ID	ord-820c0849e98843d9b97b4cf891d67d28
Source note	uspto-grants-2006_01