HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 5-ethyl-6,7-dihydro-1-benzofuran-4(5H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | 4,5,6,7-Tetrahydro-1-benzofuran-4-one | HCID 2733541 | — |
| Reactant | 5-methyl-6,7-dihydro-1-benzothiophen-4(5H)-one | HCID 15411508 | — |
| Product | 5-ethyl-6,7-dihydro-1-benzofuran-4(5H)-one | HCID 22147457 | — |
Reaction Steps
Following the procedure for the preparation of 5-methyl-6,7-dihydro-1-benzothiophen-4(5H)-one but substituting 6,7-dihydro-1-benzofuran-4(5H)-one and ethyl iodide and making non-critical variations provided the title compound as a oil: 1H NMR (CDCl3) δ 1.00, 1.54, 1.95, 2.29, 2.91, 6.67, 7.3; MS (EI) m/z (rel. intensity) 164 (M+, 36), 164 (36), 136 (90), 135 (24), 108 (76), 88 (13), 86 (69), 84 (99), 80 (58), 52 (21), 51 (57). HRMS (FAB) calcd for C10H12O2+H 165.0916, found 165.0919. Anal. Calcd for C10H12O2: C, 73.15; H, 7.37. Found: C, 72.81; H, 7.60.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992087B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-0d68b60a105a4e8bb10cb2f003a779aa |
| Source note | uspto-grants-2006_01 |