HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,5,6,7-Tetrahydro-4-oxothionaphthene → 4,5,6,7-Tetrahydro-1-benzothiophen-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,5,6,7-Tetrahydro-4-oxothionaphthene | HCID 83418 | — |
| Reactant | 4,5,6,7-Tetrahydro-1-benzofuran-4-amine | HCID 18525171 | — |
| Product | 4,5,6,7-Tetrahydro-1-benzothiophen-4-amine | HCID 4216372 | — |
Reaction Steps
Following the procedure for the preparation of 4,5,6,7-tetrahydro-1-benzofuran-4-amine but substituting 6,7-dihydro-1-benzothiophen-4(5H)-one and making non-critical variations provided the title compound as a oil: 1H NMR (400 MHz, CDCl3) δ 7.09, 7.02, 3.95, 2.79, 2.03, 1.85, 1.62; 13C NMR (100 MHz, CDCl3) δ 140.51, 137.18, 126.77, 122.66, 47.96, 34.24, 25.48, 21.48;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992087B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-b300663d8bdc4ffcbe808d9c98e0762b |
| Source note | uspto-grants-2006_01 |