HuagongsheHuagongshe Chemistry Print Report · For research reference only
6,7-dihydro-5H-cyclopenta(b)pyridin-7-amine → N-(3,6-diethylpyrazin-2-yl)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6,7-dihydro-5H-cyclopenta(b)pyridin-7-amine | HCID 12099065 | — |
| Reactant | (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol | HCID 58583341 | — |
| Product | N-(3,6-diethylpyrazin-2-yl)-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine | HCID 22147455 | — |
Reaction Steps
Following the procedure for the preparation of (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol but substituting 6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine and making non-critical variations provided the title compound as a oil: 1H NMR (300 MHz, CDCl3) δ) 8.46, 7.60, 7.17, 5.37, 5.25, 3.11-2.95, 2.75-2.61, 1.94-1.81, 1.36-1.26; (MS/CI) calcd for C16H20N4+H 269.4, found 269.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992087B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-ad54432e44a04a4998260c575e58a341 |
| Source note | uspto-grants-2006_01 |