HuagongsheHuagongshe Chemistry Print Report · For research reference only
6,7-Dihydro-5H-cyclopenta[b]pyridin-5-amine → N-(3,6-diethylpyrazin-2-yl)-6,7-dihydro-5H-cyclopenta[b]pyridin-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6,7-Dihydro-5H-cyclopenta[b]pyridin-5-amine | HCID 22147391 | — |
| Reactant | (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol | HCID 58583341 | — |
| Product | N-(3,6-diethylpyrazin-2-yl)-6,7-dihydro-5H-cyclopenta[b]pyridin-5-amine | HCID 22147523 | — |
Reaction Steps
Following the procedure for the preparation of (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol but substituting 6,7-dihydro-5H-cyclopenta[b]pyridin-5-amine and making non-critical variations provided the title compound as a oil: 1H NMR (400 MHz, CDCl3) δ) 8.48, 7.73, 7.66, 7.14, 5.82, 4.54, 3.22-3.07, 2.79, 2.70-2.57, 1.94 1.36-1.27; HRMS (FAB) calcd for C16H20N4+H 269.1766, found 269.1763.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992087B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-692c64eaf10c4f8fb3dd4c71471352ec |
| Source note | uspto-grants-2006_01 |