HuagongsheHuagongshe Chemistry Print Report · For research reference only
6,7-Dihydro-5H-cyclopenta[b]pyridin-5-amine → 6-Ethyl-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6,7-Dihydro-5H-cyclopenta[b]pyridin-5-amine | HCID 22147391 | — |
| Reactant | (NZ)-N-(6-ethyl-5,6-dihydrocyclopenta[b]pyridin-7-ylidene)hydroxylamine | HCID 136010242 | — |
| Product | 6-Ethyl-6,7-dihydro-5H-cyclopenta[b]pyridin-7-amine | HCID 22147344 | — |
Reaction Steps
Following the procedure for the preparation of 6,7-dihydro-5H-cyclopenta[b]pyridin-5-amine but substituting (7Z)-6-ethyl-5,6-dihydro-7H-cyclopenta[b]pyridin-7-one oxime and making non-critical variations provided the title compound as a oil: 1H NMR (400 MHz, CDCl3) δ) 8.40, 7.51, 7.10, 4.30, 3.95, 3.07, 2.95, 2.74, 2.50, 2.38, 2.03-1.93, 1.75, 1.57, 1.40, 1.09-0.97; HRMS (FAB) calcd for C10H14N2+H 163.1235, found 163.1229.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992087B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-a7957ba3eafa4d95a5a5469214005b2d |
| Source note | uspto-grants-2006_01 |