6,7-Dihydro-5H-cyclopenta[b]pyridin-5-amine → 2-Ethyl-2,3-dihydro-1H-inden-1-amine
Reaction equation
N1C=CC=C2C(N)CCC=12.[CH2:11]([CH:13]1[CH2:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[C:14]1=[N:22]O)[CH3:12]>>[CH2:11]([CH:13]1[CH2:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]1[NH2:22])[CH3:12]Participants
3
Procedure
Following the procedure for the preparation of 6,7-dihydro-5H-cyclopenta[b]pyridin-5-amine but substituting 2-ethyl-2,3-dihydro-1H-inden-1-one oxime and making non-critical variations provided the title compound as a colorless oil.
Sources & evidence
- ORD record
- ord-82ba1dedd76d48a5a610aef214a71d58
- Source dataset
- uspto-grants-2006_01
- Patent number
- US06992087B2
Reaction notes
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