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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1612263Generated: October 25, 2026

2-Ethyl-2,3-dihydro-1H-inden-1-amine → 3,6-diethyl-N-(2-ethyl-2,3-dihydro-1H-inden-1-yl)pyrazin-2-amine

https://huagongshe.com/reaction/1612263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Ethyl-2,3-dihydro-1H-inden-1-amineHCID 12337214—
Reactant(1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-olHCID 58583341—
Product3,6-diethyl-N-(2-ethyl-2,3-dihydro-1H-inden-1-yl)pyrazin-2-amineHCID 22147273—

Reaction Steps

Following the procedure for the preparation of (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol but substituting 2-ethylindan-1-amine and making non-critical variations provided the title compound as a yellow oil. MS (ESI+) for m/z 296.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06992087B2
Source datasetuspto-grants-2006_01
ORD IDord-c96acdaac877444f8585a179535fb282
Source noteuspto-grants-2006_01