(1R,2S)-1-{[5-(2,4-dichlorophenyl)-3,6-diethylpyrazin-2-yl]amino}-2,3-dihydro-1H-inden-2-ol → HCID 58583381, compound

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Reaction Steps

Following the procedure for the preparation of (1R,2S)-1-{[5-(2,4-dichlorophenyl)-3,6-diethylpyrazin-2-yl]amino}-2,3-dihydro-1H-inden-2-ol but substituting (+/−)-5-bromo-3,6-diethyl-N-[cis-2-ethyl-2,3-dihydro-1H-inden-1-yl]pyrazin-2-amine and making non-critical variations provided the title compound as a light yellow semi-solid. IR (liq.) 3452, 2965, 2934, 2874, 1589, 1566, 1551, 1495, 1470, 1392, 1377, 1203, 1175, 1101, 752 cm−1; OAMS supporting ions at: ESI+ 439.8; HRMS (FAB) calcd for C25H27CL2N3+H1 440.1660, found 440.1648. Anal. Calcd for C25H27Cl2N3: C, 68.18; H, 6.18; N, 9.54. Found: C, 68.33; H, 6.36; N, 9.30.

Provenance & Evidence