HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl N-{2-[(tert-butoxycarbonyl)amino]butanoyl}alaninate → methyl N-(2-aminobutanoyl)alaninate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl N-{2-[(tert-butoxycarbonyl)amino]butanoyl}alaninate | HCID 86588879 | — |
| Reactant | methyl(L-alanylamino)(cyclopropyl)acetate hydrochloride | HCID 86588880 | — |
| Product | methyl N-(2-aminobutanoyl)alaninate hydrochloride | HCID 86588882 | — |
Reaction Steps
Following the procedure for the preparation of methyl (L-alanylamino)(cyclopropyl)acetate hydrochloride but substituting methyl N-{2-[(tert-butoxycarbonyl)amino]butanoyl}alaninate and making non-critical variations provided the title compound as a solid: 1H NMR (DMSO-d6) δ 0.86-0.92, 1.39-1.41, 1.62-1.82, 3.64, 3.92, 4.18-4.23, 8.36. 8.92.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992087B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-9db6110c9c4142eca8b31f10c90db01e |
| Source note | uspto-grants-2006_01 |