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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1612332Generated: November 1, 2026

HCID 22147494, compound → HCID 58583262, compound

https://huagongshe.com/reaction/1612332

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22147494HCID 22147494—
Reactant(1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-olHCID 58583341—
ProductHCID 58583262HCID 58583262—

Reaction Steps

Following the procedure for the preparation of (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol but substituting 3-chloro-5-cyclopropyl-2-ethylpyrazine and making non-critical variations provided the title compound as a solid: 1H NMR (CDCl3) δ 0.92-0.95, 1.31-1.35, 1.93, 2.59-2.70, 3.03-3.10, 3.22-3.30, 4.74, 4.91, 5.49-5.52, 7.28-7.32, 7.82; MS (ESI+) for C18H21N3O m/z 296 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06992087B2
Source datasetuspto-grants-2006_01
ORD IDord-7cf8c3296fbf4cc880ad921ea948458c
Source noteuspto-grants-2006_01