HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(2,4-dichlorophenyl)-N-[(1R,2S)-2-ethoxy-2,3-dihydro-1H-inden-1-yl]-3,6-diethylpyrazin-2-amine → HCID 58583467, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(2,4-dichlorophenyl)-N-[(1R,2S)-2-ethoxy-2,3-dihydro-1H-inden-1-yl]-3,6-diethylpyrazin-2-amine | HCID 10217073 | — |
| Reactant | HCID 58583366 | HCID 58583366 | — |
| Product | HCID 58583467 | HCID 58583467 | — |
Reaction Steps
Following the procedure for the preparation of 5-(2,4-dichlorophenyl)-N-[(1R,2S)-2-ethoxy-2,3-dihydro-1H-inden-1-yl]-3,6-diethylpyrazin-2-amine but substituting (1R,2S)-1-[(5-bromo-3-cyclopropyl-6-ethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol and making non-critical variations provided the title compound as a solid: 1H NMR (CDCl3) δ 0.94-1.02, 1.14-1.19, 1.26-1.30, 1.68-1.86, 2.06, 2.28-2.49, 3.08-3.32, 4.06-4.18, 4.83-4.87, 5.49, 5.62-5.66, 7.27-7.50; MS (ESI+) for C24H23Cl2N3O m/z 440(MH)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992087B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-0770dda7fa824b6e8c15d35a51428485 |
| Source note | uspto-grants-2006_01 |